Original Contribution Prediction of Coronary Heart Disease Risk using a Genetic Risk Score: The Atherosclerosis Risk in Communities Study
نویسندگان
چکیده
1 Human Genetics Center and Division of Epidemiology, University of Texas Health Science Center at Houston, Houston, TX. 2 Celera, Alameda, CA. 3 Collaborative Studies Coordinating Center, University of North Carolina, Chapel Hill, NC. 4 Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH. 5 Cardiovascular Research Institute, University of California, San Francisco, CA. 6 Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN. 7 Texas Heart Institute, Houston, TX.
منابع مشابه
Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study.
Recent studies have evaluated whether incorporating nontraditional risk factors improves coronary heart disease (CHD) prediction models. This 1986-2001 US study aggregated the contribution of multiple single nucleotide polymorphisms into a genetic risk score (GRS) and assessed whether the GRS plus traditional risk factors predict CHD better than traditional risk factors alone. The Atheroscleros...
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تاریخ انتشار 2007